The Bills are seemingly getting healthy heading into the matchup, as linebacker Matt Milano and receiver Keon Coleman both practiced during the week. Milano is officially questionable for the matchup.

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

The Buffalo Bills are in line to accomplish a feat no other NFL club has completed in 15 years – clinch their division after ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

The Bills will not have one of their key offensive players for Sunday’s game against the 49ers, though they could get one of ...

T he Buffalo Bills are coming off their bye week and getting set for the final six-game stretch of the season, beginning at ...

Patriots offensive lineman Cole Strange won’t play this Sunday. So when will he finally make his return to the field?

The NFL playoff picture isn't moving drastically after Thanksgiving, but the Dolphins' loss Thursday night means the Bills ...

The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

The snow may taper off by kickoff, but conditions ahead of the Bills game Sunday night could still make travel difficult.

"GMFB" on what would a loss mean for the San Francisco 49ers in Week 13 vs. the Buffalo Bills. "GMFB" debates is Denver ...

Dontayvion Wicks gets a bump up the depth chart with fellow WR Romeo Doubs out for the Thanksgiving game. His snap counts ...