For decades, depression treatment has focused almost entirely on the brain, with drugs designed to tweak neurotransmitters ...

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has provided the ...

When it comes to treating depression, one size definitely does not fit all, and they're not the answer for everyone.

SSRIs enhance CD8 T cell antitumor activity by inhibiting SERT, an immune checkpoint in tumors, suggesting potential repurposing for cancer immunotherapy. High intratumoral SERT levels correlate with ...

In our day-to-day lives, we're constantly making a slew of decisions, from immediate matters to prospects on the far horizon. But the evolutionary nuts-and-bolts of how our brains weigh these numerous ...

The intricate web of chemical messengers that facilitate communication between neurons represents one of the body’s most complex and fascinating systems. These neurotransmitters, including serotonin, ...

Loss of the "happiness" brain hormone serotonin might play a role in the decline of brain function as a person ages, a new study reports. People with mild cognitive impairment (MCI) had up to 25% ...

Trigonelline is derived from coffee; researchers have found that it improves spatial learning and memory in senescence-accelerated mice. The study also suggested that this effect results from ...

Serotonin is a chemical produced mostly in our digestive tract. 1 Despite its humble beginnings in the gut, serotonin has the important job of deciding which brain cells to "turn off" (inhibit) during ...

Low levels of serotonin in the brain are seen as a possible cause of depression and many antidepressants act by blocking a protein that transports serotonin away from the nerve cells. A brain imaging ...