By firing coach Pete Carroll and defining their chain of command, the Raiders have a chance to make real change after a 3-14 ...

Two of the NFL's best headlined a Week 16 matchup with playoff implications, as Christian McCaffrey and the San Francisco 49ers defeated Jonathan Taylor and the Indianapolis Colts, 48-27, at Lucas Oil ...

Philip Rivers returns to Lucas Oil Stadium tonight to try and keep the Indianapolis Colts' playoff hopes alive against the San Francisco 49ers. My 49ers vs. Colts predictions and NFL picks for Monday ...

The San Francisco 49ers hit the road in Week 16 for a “Monday Night Football” showdown with veteran gunslinger Philip Rivers and the Indianapolis Colts. The game is scheduled to start at 8:15 p.m. ET ...

ESPN debuted a brand new altcast during the Week 16 Monday Night Football game between the Indianapolis Colts and San Francisco 49ers. The MNF Playbook feed showcased advanced stats and an analytics ...

CB Garrett Williams is feared to have torn his Achilles in Sunday's loss to the Falcons, NFL Network Insiders Ian Rapoport and Mike Garafolo reported Monday. Williams will have an MRI to confirm the ...

The San Francisco 49ers will visit the Indianapolis Colts for Monday Night Football. This Week 16 game is scheduled for Monday, December 22, 2025, at 8:15 p.m. The matchup will be broadcast on ESPN ...

The Indianapolis Colts (8-6) host the San Francisco 49ers (10-4) on Monday, December 22, 2025 at Lucas Oil Stadium and will aim to halt a four-game losing streak. Here are best bets recommendations.

Who will win on Monday Night Football in NFL Week 16? The San Francisco 49ers and Indianapolis Colts play on Monday, Dec. 22 at the Colts' Lucas Oil Stadium in a game on the NFL Week 16 schedule. What ...

The Miami Dolphins hold a 6-9 record with two games remaining in the season. The Dolphins are ranked 22nd in the Week 17 NFL Power Rankings. Quinn Ewers is expected to start at quarterback in place of ...

The San Francisco 49ers (10-4) will be aiming to extend a four-game winning run against the Indianapolis Colts (8-6). The 49ers are the favorites, expected to win by at least a field goal but less ...

Caleb Williams has led the Bears to the playoffs in his second NFL season. Michael Reaves / Getty Images By Jayna Bardahl, Kevin Fishbain and Vic Tafur The Chicago Bears and San Francisco 49ers are ...