The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

Buffalo Bills coach Sean McDermott ruled out Dalton Kincaid from playing against San Francisco on Sunday night, while holding ...

The Bills are seemingly getting healthy heading into the matchup, as linebacker Matt Milano and receiver Keon Coleman both ...

Miami Dolphins linebacker Jordyn Brooks didn’t hold anything back about his team's effort after a 30-17 loss at frigid Green ...

The decision to fire Eberflus marks the first time in franchise history that the Bears have parted ways with a head coach in ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

The Buffalo Bills came soaring into their bye week during NFL Week 13 riding a six-game winning streak to a 9-2 record. They ...

With Buffalo’s collective belly full of holiday treats, it’s time to get back to business as the Bills get set to take on the ...

Los Angeles Chargers (7-4) at Atlanta Falcons (6-5), 1 p.m. ET, FOX Atlanta holds a one-game lead over the Tampa Bay Buccaneers in the NFC South but lost the last ...

The Buffalo Bills are in line to accomplish a feat no other NFL club has completed in 15 years – clinch their division after ...

The Bills will not have one of their key offensive players for Sunday’s game against the 49ers, though they could get one of ...