The 49ers’ situation could grow even more dire if Brock Purdy isn’t ready for Sunday’s must-win matchup against the Buffalo ...

The 49ers listed Brock Purdy as a limited participant while Nick Bosa and Trent Williams were among those not practicing ...

The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December 1, ...

According to Matt Barrows of The Athletic, San Francisco 49ers quarterback Brock Purdy (shoulder) remained a limited ...

49ers quarterback Brock Purdy (shoulder) remained limited in practice a second consecutive day. It is unknown how much ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Montgomery found the end zone shortly before halftime to give the Lions a 14-6 lead, the fifth time he's scored a touchdown ...

Purdy (shoulder) was listed as limited on Thursday's injury report, Matt Barrows of The Athletic reports. Purdy so far is mimicking last week's practice regimen after going down as a limited ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San ...