Following their high-profile victory over the AFC-leading Chiefs, the Bills went off the NFL radar for their much-needed Week ...

A Super Bowl between the Buffalo Bills and the Detroit Lions would be a contest about much more than just football.

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

Sunday could be the day Douglas has been waiting for -- because Milano is closing in on his return. The 30-year-old was a full participant in practice on Wednesday. He wore a red non-contact jersey ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Offensive tackle Trent Williams, in pain on a knee scooter, is doubtful for Sunday's game vs. the Buffalo Bills, a blow for ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

After halting construction this spring on a $175 million project to construct an osteopathic medical school on Buffalo’s West ...

When we last asked you how confident you were in the direction of the Buffalo Bills, the results returned a rather ...

The Browns' win in the snow over the Steelers was just latest in a history full of games where the weather played a major role.