Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

The nuclei of most human cells contains the entire genome, which would have a length of about six feet if it was fully extended. So this DNA has to be carefully compacted in cells, while still ...

High-Resolution Imaging Reveals Droplet Structure Using advanced imaging tools at Janelia, the researchers captured the most detailed views to date of how molecules are arranged inside synthetic ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...