Our discovery set comprised 31 pRCCs and paired normal tissue or peripheral blood (Table 1). Three tumours were separate foci from case GK116; these appeared to be grossly distinct lesions and were ...

Regional variation in mutation rates is an important phenomenon that affects genome evolution. It is determined by features of genomic landscape, with chromatin having an important influence. Pairwise ...

Researchers discover unexpected patterns in mutation risks across individuals, uncovering 13 distinct genomic patterns. The study provides crucial insights into cancer evolution, identifying the genes ...

An international study has identified more than 50 genes on the X chromosome in which mutations may cause poor sperm production. Nearly half of all men with low or zero sperm count have no medical ...