Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Cells organize their molecules into distinct functional areas. While textbooks usually refer to membrane-bound organelles ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...

All modern multicellular life — all life that any of us regularly see — is made of cells with a knack for compartmentalization. Recent discoveries are revealing how the first eukaryote got its start.

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...

One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes – be they organs, wings, or limbs. Scientists ...

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in which aging cells change how they function—is associated with human brain ...

These include stress granules and proteasome storage granules (PSGs). In the past, these membraneless organelles were only visible as “droplets” using a fluorescence microscope. Now, researchers from ...