Endosomal trafficking and protein sorting constitute fundamental processes that govern the intracellular localisation and recycling of membrane proteins in eukaryotic cells. Endosomes act as central ...
Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in ...
Make way, APP, PS1, PS2. A fourth gene, SORL1, is joining you on the podium of infamy. For years, researchers have steadily built the case that SORL1 is the fourth familial, sometimes even ...
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