The framework predicts how proteins will function with several interacting mutations and finds combinations that work well together.

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for scientists to study their individual units without altering their natural structure.

Protein function prediction and annotation represent critical challenges in the post‐genomic era. As high‐throughput sequencing continues to generate vast amounts of protein data, computational ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe.

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but necessary to explain cosmology. Astronomy, however, isn't the only field with ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

While the amount of protein needed varies, the general guideline from organizations like the US National Academies (Dietary ...