For microarrays, the transition from research to clinical and diagnostic applications is well underway. Microarrays use a range of specific probes that are immobilized in known locations on a support ...

Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...

Patient-tailored medicine can be defined as the selection of specific therapeutics to treat disease in a particular individual based on genetic, genomic or proteomic information. While individualized ...

A study funded by the National Cancer Institute, part of the National Institutes of Health, shows for the first time that microarray data generated in different laboratories can produce highly ...

A recent study highlights how DNA microarray technology enables high-throughput gene analysis, supporting variation detection, expression ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

The Dutch Council for Accreditation (RvA) has accredited the Array facility of the Genome Diagnostic section of the University Medical Centre Utrecht with NEN-EN-ISO 15189. This is the first such ...

Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on a ...

Although the superiority of expression-based biomarkers, as compared with traditional clinical staging, has been disputed, 33 a nationwide clinical trial is under way in the Netherlands in which ...