Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...

Researchers uncovered how cells coordinate genetic compensation when faulty mRNA is degraded. Small RNA fragments act as sequence “addresses” that recruit ILF3 to activate related backup genes.

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...