Figure 1: Hsk1–Dfp1 interacts with and phosphorylates Swi6. Figure 2: S-phase activity of Hsk1–Dfp1 is required for equal chromosome segregation. The activity of Hsk1–Dfp1 on Swi6 after its initial ...

A recent study In Press at the Journal of Cell Biology reports that herpes simplex virus 1 (HSV-1) exploits heterochromatin to successfully exit the nucleus. The heterochromatin markers macroH2A1 and ...

In Saccharomyces cerevisiae, heterochromatin structures required for transcriptional silencing of the HML and HMR loci are duplicated in coordination with passing DNA replication forks. Despite major ...

Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...

Chromatin consists of the DNA molecule and numerous proteins, including histones, which act as packaging proteins. In contrast to the easily accessible euchromatin, which contains the majority of ...

Two recent studies show that heterochromatin domain formation is driven by phase separation—a process in which proteins self-organize into liquid-like droplets that grow and fuse, allowing certain ...

Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A researcher disputes that belief and hopes to change the ...

This press release is available in German. To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly ...

image: Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A University of Arizona researcher disputes that ...