Ribosomes, the cell's protein-making factories, consume large amounts of energy as they build the proteins that keep cells alive and functioning. When cells experience stress—such as lack of nutrients ...

Cell-free protein synthesis (CFPS) represents a transformative technology in which the molecular machinery of transcription and translation is extracted from living cells and employed in a controlled ...

Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories together to survive when energy is low.

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.

The yeast Kluyveromyces lactis (K. lactis) could become a highly productive, sustainable, cost-effective energy source for cell-free protein synthesis (CFPS) as biopharmaceutical manufacturers strive ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Ginkgo Bioworks Holdings (DNA) announced on Thursday that, in collaboration with Microsoft (MSFT)-backed OpenAI (OPENAI), it has designed an AI system that can lower costs in cell-free protein ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...