Before you make any Week 13 NFL picks, be sure to see the exact NFL score predictions from SportsLine expert Eric Cohen. Cohen, a SportsLine NFL expert and host of the Friday "Early Edge NFL Props Show" on SportsLine's YouTube page,

As much has changed in the NFL this season, it looks like the Kansas City Chiefs and Buffalo Bills are once again on a collision course to decide each other's f

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with just the front four. Buffalo is Top 10 in EPA allowed per pay and very stingy against the run, sitting seventh in run-stop win rate at ESPN and No. 9 in opponent success rate per handoff.

Aaron Rodgers and the New York Jets have lost seven of their last eight games and now will host the Seattle Seahawks for a cross-conference matchup in Week 13. The Seahawks have won five straight against the Jets and Seattle is a 1.

NFL Week 13 picks, predictions, win probabilities for Chargers vs Falcons, Steelers vs Bengals, Eagles vs Ravens, 49ers vs Bills, this week's games.

What do NFL betting odds say about each game this week?Start the day smarter. Get all the news you need in your inbox each morning. Who are the favorites on Thanksgiving Day? Who is favored on Black Friday,

It’s Thanksgiving Week, and all 32 NFL teams are in action. While the Detroit Lions and Kansas City Chiefs are both favored by double-digits, 13 of the other 14 games have point spreads of less than seven points.