The highest snow accumulations are expected east of Lake Ontario, where some isolated areas could get up to 60 inches of lake effect snow early in the week.

The first major lake effect snow system of the season hit parts of Pennsylvania and western New York on Saturday, with totals expected to exceed 5 feet. Plows have been working furiously to clear the roads,

An arctic blast of severe cold and snow is creating hazardous conditions across the Great Lakes region over the next two days, according to the US Weather Prediction Center, potentially disrupting the plans of millions traveling the roads and skies.