For the second time in six years, all that stands in Notre Dame’s way from a spot in the College Football Playoff is a road trip to rival USC.

The USC Trojans host the Notre Dame Fighting Irish at the Los Angeles Memorial Coliseum on Saturday afternoon. Kickoff is set for 12:30 p.m PT on CBS. USC clinc

Notre Dame faces a tough test on the road at USC, but the defense should hold enough to give the Irish a close win. The Notre Dame at USC game starts at 3:30 EST and can be seen on CBS. Get more betting analysis and predictions at Sportsbook Wire.