Having a 5-6 record entering Week 13 isn't how the San Francisco 49ers drew it up. Injuries have played a part in their ...

Brock Purdy remained limited in a Thanksgiving Day practice, keeping his status in doubt for the 49ers’ game Sunday at ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

San Francisco 49ers offensive tackle Trent Williams was seen in the locker room on Wednesday using a scooter as he recovers ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

The 49ers were a perennial power as they won five Super Bowls between 1981 and 1994 and reached the NFC Championship Game ...